Targeted Therapies in Advanced Cholangiocarcinoma: A Focus on FGFR Inhibitors.
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ABSTRACT:
SUBMITTER: Rizzo A
PROVIDER: S-EPMC8151905 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Publications
Targeted Therapies in Advanced Cholangiocarcinoma: A Focus on FGFR Inhibitors.
Medicina (Kaunas, Lithuania) 20210508 5
Despite advanced diseases continuing to be associated with grim prognoses, the past decade has witnessed the advent of several novel treatment options for cholangiocarcinoma (CCA) patients. In fact, CCA has emerged as a heterogeneous group of malignancies harboring potentially druggable mutations in approximately 50% of cases, and thus, molecularly targeted therapies have been actively explored in this setting. Among these, fibroblast growth factor receptor (FGFR) inhibitors have reported import ...[more]
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