Clinical significance of circulating tumour cells and Ki-67 in renal cell carcinoma.

ABSTRACT:

Background

Renal cell carcinoma (RCC) is a common malignant tumour of the genitourinary system. We aimed to analyse the potential value of metastasis-related biomarkers, circulating tumour cells (CTCs) and the proliferative marker Ki-67 in the diagnosis of RCC.

Methods

Data from 24 laparoscopic radical nephrectomies (RNs) and 17 laparoscopic partial nephrectomies (PNs) were collected in 2018. The numbers and positive rates of CTCs and circulating tumour microemboli (CTM) in the peripheral blood were obtained at three different time points: just before surgery, immediately after surgery and 1 week after surgery. Ki-67 protein expression was evaluated in the RCC tissue by immunohistochemistry.

Results

Except for the statistically significant association between the preo

SUBMITTER: Song J 

PROVIDER: S-EPMC8152311 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature