Ontology highlight
ABSTRACT:
SUBMITTER: Calles M
PROVIDER: S-EPMC8152698 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Calles María M Puigcerver Julio J Alonso Diego A DA Alajarin Mateo M Martinez-Cuezva Alberto A Berna Jose J
Chemical science 20200311 14
The synthesis of a pair of switchable interlocked prolinamides and their use as organocatalysts in three different enamine-activated processes are reported. A diacylaminopyridine moiety was incorporated into the thread for directing [2]rotaxane formation further allowing the association of complementary small molecules. The rotaxane-based systems were tested as organocatalysts in asymmetric enamine-mediated processes, revealing a significantly improved catalytic ability if compared with the non- ...[more]