Importance of the Primary Motor Cortex in Development of Human Hand/Finger Dexterity.

ABSTRACT: Hand/finger dexterity is well-developed in humans, and the primary motor cortex (M1) is believed to play a particularly important role in it. Here, we show that efficient recruitment of the contralateral M1 and neuronal inhibition of the ipsilateral M1 identified by simple hand motor and proprioceptive tasks are related to hand/finger dexterity and its ontogenetic development. We recruited healthy, right-handed children (n = 21, aged 8-11 years) and adults (n = 23, aged 20-26 years) and measured their brain activity using functional magnetic resonance imaging during active and passive right-hand extension-flexion tasks. We calculated individual active control-related activity (active-passive) to evaluate efficient brain activity recruitment and individual task-related deactiv

SUBMITTER: Naito E 

PROVIDER: S-EPMC8152843 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature