Multisystemic Increment of Cortical Thickness in Congenital Blind Children.

ABSTRACT: It has been shown that the total or partial lack of visual experience is associated with a plastic reorganization at the brain level, more prominent in congenital blind. Cortical thickness (CT) studies, to date involving only adult subjects, showed that only congenital blind have a thicker cortex than age-matched sighted population while late blind do not. This was explained as a deviation from the physiological mechanism of initial neural growth followed by a pruning mechanism that, in congenital blind children, might be reduced by their visual deprivation, thus determining a thicker cortex. Since those studies involved only adults, it is unknown when these changes may appear and whether they are related to impairment degree. To address this question, we compared the CT among 28 children,

SUBMITTER: Inuggi A 

PROVIDER: S-EPMC8152892 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature