Automatic Segmentation of the Dorsal Claustrum in Humans Using in vivo High-Resolution MRI.

ABSTRACT: The claustrum is a thin sheet of neurons enclosed by white matter and situated between the insula and the putamen. It is highly interconnected with sensory, frontal, and subcortical regions. The deep location of the claustrum, with its fine structure, has limited the degree to which it could be studied in vivo. Particularly in humans, identifying the claustrum using magnetic resonance imaging (MRI) is extremely challenging, even manually. Therefore, automatic segmentation of the claustrum is an invaluable step toward enabling extensive and reproducible research of the anatomy and function of the human claustrum. In this study, we developed an automatic algorithm for segmenting the human dorsal claustrum in vivo using high-resolution MRI. Using this algorithm, we segmented the dorsal claust

SUBMITTER: Berman S 

PROVIDER: S-EPMC8153060 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature