Genomic and Metabolomic Analysis of the Potato Common Scab Pathogen Streptomyces scabiei.

ABSTRACT: Streptomyces scabiei is a key causative agent of common scab disease, which causes significant economic losses to potato growers worldwide. This organism produces several phytotoxins that are known or suspected to contribute to host-pathogen interactions and disease development; however, the full metabolic potential of S. scabiei has not been previously investigated. In this study, we used a combined metabolomic and genomic approach to investigate the metabolites that are produced by S. scabiei. The genome sequence was analyzed using antiSMASH and DeepBGC to identify specialized metabolite biosynthetic gene clusters. Using untargeted liquid chromatography-coupled tandem mass spectrometry (LC-MS²), the metabolic profile of S. scabiei was compared after

SUBMITTER: Liu J 

PROVIDER: S-EPMC8153979 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature