No Association Between Statin Use and the Prognosis of Endometrial Cancer in Women With Type 2 Diabetes.

ABSTRACT: Preclinical studies have suggested statins have antiproliferative and anti-metastatic effects on endometrial cancer cells. Similarly, most previous epidemiological studies have reported a better prognosis of endometrial cancer in patients who used statins. In this study, we explored the role of statins in the prognosis of endometrial cancer in women with type 2 diabetes in a hospital-based cohort. This retrospective cohort consisted of 119 women with type 2 diabetes who were diagnosed and treated for endometrial cancer at Oulu University Hospital, Finland, between 2007 and 2014. The patients were classified as statin users (n = 58) and nonusers (n = 61) based on the type of medication they were using at the time of endometrial cancer diagnosis. Statin use showed no associatio

SUBMITTER: Urpilainen E 

PROVIDER: S-EPMC8155720 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature