Assessment of the Implementation of Pharmacogenomic Testing in a Pediatric Tertiary Care Setting.

ABSTRACT:

Importance

Pharmacogenomic (PGx) testing provides preemptive pharmacotherapeutic guidance regarding the lack of therapeutic benefit or adverse drug reactions of PGx targeted drugs. Pharmacogenomic information is of particular value among children with complex medical conditions who receive multiple medications and are at higher risk of developing adverse drug reactions.

Objectives

To assess the implementation outcomes of a PGx testing program comprising both a point-of-care model that examined targeted drugs and a preemptive model informed by whole-genome sequencing that evaluated a broad range of drugs for potential therapy among children in a pediatric tertiary care setting.

Design, setting, and participants

This cohort study was conducted at The Hospital for Sick C

SUBMITTER: Cohn I 

PROVIDER: S-EPMC8155824 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature