Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Pinedo U
PROVIDER: S-EPMC8155872 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Gómez-Pinedo Ulises U García-Ávila Yolanda Y Gallego-Villarejo Lucía L Matías-Guiu Jordi A JA Benito-Martín María Soledad MS Esteban-García Noelia N Sanclemente-Alamán Inmaculada I Pytel Vanesa V Moreno-Jiménez Lidia L Sancho-Bielsa Francisco F Vidorreta-Ballesteros Lucía L Montero-Escribano Paloma P Matías-Guiu Jorge J
International journal of molecular sciences 20210514 10
<h4>Introduction</h4>AQP4 (aquaporin-4)-immunoglobulin G (IgG)-mediated neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disease that affects the central nervous system, particularly the spinal cord and optic nerve; remyelination capacity in neuromyelitis optica is yet to be determined, as is the role of AQP4-IgG in cell differentiation.<h4>Material and methods</h4>We included three groups-a group of patients with AQP4-IgG-positive neuromyelitis optica, a healthy g ...[more]