Use of viral load to improve survey estimates of known HIV-positive status and antiretroviral treatment coverage.

ABSTRACT:

Objective

To compare alternative methods of adjusting self-reported knowledge of HIV-positive status and antiretroviral (ARV) therapy use based on undetectable viral load (UVL) and ARV detection in blood.

Design

Post hoc analysis of nationally representative household survey to compare alternative biomarker-based adjustments to population HIV indicators.

Methods

We reclassified HIV-positive participants aged 15-64 years in the 2012 Kenya AIDS Indicator Survey (KAIS) who were unaware of their HIV-positive status by self-report as aware and on antiretroviral treatment if either ARVs were detected or viral load was undetectable (<550 copies/ml) on dried blood spots. We compared self-report to adjustments for ARV measurement, UVL, or both.

Results

Treatment coverag

SUBMITTER: Young PW 

PROVIDER: S-EPMC8157159 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature