Adaptation and validation of simple tools to screen and monitor for oral PrEP adherence.

ABSTRACT:

Introduction

Oral, vaginal and other pre-exposure prophylaxis (PrEP) products for HIV prevention are in various stages of development. Low adherence poses a serious challenge to successful evaluation in trials. In a previous study, we developed tools to screen for general adherence and specifically monitor intravaginal ring adherence within the context of HIV prevention clinical trials. This study aimed to further validate the screening tool and to adapt and provide initial psychometric validation for an oral pill monitoring tool.

Materials and methods

We administered a cross-sectional survey between June and October 2018 at a trial site located near Cape Town, South Africa, and another in Thika, Kenya, with 193 women who had experience using daily oral pills. We fit confirm

SUBMITTER: Zissette S 

PROVIDER: S-EPMC8158999 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature