Material decomposition using iodine quantification on spectral CT for characterising nodules in the cirrhotic liver: a retrospective study.

ABSTRACT:

Background

There is limited scientific evidence on the potential of spectral computed tomography (SCT) for differentiation of nodules in the cirrhotic liver. We aimed to assess SCT-generated material density (MD) parameters for nodule characterisation in cirrhosis.

Methods

Dynamic dual-energy SCT scans of cirrhotic patients performed over 3 years were retrospectively reviewed. They were classified as hepatocellular carcinoma (HCC), regenerative or indeterminate, according to the European Association for the Study of the Liver criteria. MD maps were generated to calculate the area under the curve (AUC) and cutoff values to discriminate these nodules in the hepatic arterial phase (HAP) and portal venous phase (PVP). MD maps included iodine concentration density (ICD) of the li

SUBMITTER: Laroia ST 

PROVIDER: S-EPMC8160046 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature