Sonothrombolysis in the ambulance for ST-elevation myocardial infarction: rationale and protocol.

ABSTRACT:

Background

Treatment of ST-elevation myocardial infarction (STEMI) has improved over the years. Current challenges in the management of STEMI are achievement of early reperfusion and the prevention of microvascular injury. Sonothrombolysis has emerged as a potential treatment for acute myocardial infarction, both for epicardial recanalisation as well as improving microvascular perfusion. This study aims to determine safety and feasibility of sonothrombolysis application in STEMI patients in the ambulance.

Methods

Ten patients with STEMI will be included and treated with sonothrombolysis in the ambulance during transfer to the PCI centre. Safety will be assessed by the occurrence of ventricular arrhythmias and shock during sonothrombolysis intervention. Feasibility will be as

SUBMITTER: El Kadi S 

PROVIDER: S-EPMC8160072 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature