Gut Microbiota Dysbiosis in Human Hypertension: A Systematic Review of Observational Studies.

ABSTRACT: Introduction: Hypertension is one of the major risk factors to human health and human studies on association between gut microbiota and hypertension or blood pressure have received increased attention. In the present study, we aim to evaluate gut microbiota dysbiosis in human hypertension using a method of systematic review. Methods: PubMed, EMBASE, and Web of Science databases were searched until March 2021 to identify eligible articles. Additional articles were also identified by searching specific authors in this field. Inclusion criteria were observational studies based on stool samples with hypertension group and control group. Newcastle-Ottawa quality assessment scale (NOS) was used to assess the quality of the included studies. PROSPERO registration number: CRD42020212

SUBMITTER: Guo Y 

PROVIDER: S-EPMC8160125 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature