The Behavioral Problems in 2.5-5 Years Old Children Linked with Former Neonatal/Infantile Surgical Parameters.

ABSTRACT: Studies report the link between exposure to major neonatal surgery and the risk of later neurodevelopmental disorders. The aim of this study was to find out the behavioral problem scores of 2.5-5 years old children who had undergone median/major non-cardiac surgery before the age of 90 days, and to relate these to intraoperative cerebral tissue oxygenation values (rSO₂), perioperative duration of mechanical ventilation (DMV) and doses of sedative/analgesic agents. Internalizing (IP) and externalizing problems (EP) of 34 children were assessed using the CBCL for ages 1½-5. Median (range) IP and EP scores were 8.5 (2-42) and 15.5 (5-33), respectively and did not correlate with intraoperative rSO₂. DMV correlated and was predictive for EP (β (95% CI) 0.095 (0.043; 0.148)

SUBMITTER: Rugyte D 

PROVIDER: S-EPMC8160720 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature