The influence of homeostatic mechanisms on neural regulation of food craving in anorexia nervosa.

ABSTRACT:

Background

Restrictive food intake in anorexia nervosa (AN) has been related to an overactive cognitive control network inhibiting intuitive motivational responses to food stimuli. However, the influence of short-term homeostatic signaling on the neural regulation of cue-induced food craving in AN is still unclear.

Methods

Twenty-five women with AN and 25 matched normal-weight women were examined on two occasions after receiving either glucose or water directly into their stomach using a nasogastric tube. Participants were blinded to the type of infusion. An event-related functional magnetic resonance imaging paradigm was used to investigate the effect of intestinal glucose load on neural processing during either simple viewing or distraction from food stimuli.

Results

SUBMITTER: Stopyra MA 

PROVIDER: S-EPMC8161429 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature