Ontology highlight
ABSTRACT:
SUBMITTER: Babin BM
PROVIDER: S-EPMC8161474 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Babin Brett M BM Fernandez-Cuervo Gabriela G Sheng Jessica J Green Ori O Ordonez Alvaro A AA Turner Mitchell L ML Keller Laura J LJ Jain Sanjay K SK Shabat Doron D Bogyo Matthew M
ACS central science 20210414 5
Tuberculosis (TB) is a top-ten cause of death worldwide. Successful treatment is often limited by insufficient diagnostic capabilities, especially at the point of care in low-resource settings. The ideal diagnostic must be fast, be cheap, and require minimal clinical resources while providing high sensitivity, selectivity, and the ability to differentiate live from dead bacteria. We describe here the development of a fast, luminescent, and affordable sensor of Hip1 (FLASH) for detecting and moni ...[more]