A comparison of three different approaches to defining frailty in older patients with multiple myeloma.

ABSTRACT:

Objectives

As the aging population grows, interest in applying the concept of frailty to older adults with cancer has increased. This study examines the prevalence of frailty in older patients with multiple myeloma using three frailty models.

Methods

In this secondary analysis of a prospective cohort study, 40 adults aged ≥65 with myeloma completed the Cancer and Aging Research Group geriatric assessment within three months of initial diagnosis. Geriatric assessment data was used to categorize patients' frailty status according to three indices: The International Myeloma Working Group (IMWG) Frailty Index, the Revised Myeloma Comorbidity Index (R-MCI), and the Carolina Frailty Index (CFI). Agreement between the indices was examined using Cohen's kappa.

Results

Twenty-

SUBMITTER: Isaacs A 

PROVIDER: S-EPMC8161529 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature