Salvage Treatment and Survival for Relapsed Follicular Lymphoma Following Primary Radiation Therapy: A Collaborative Study on Behalf of ILROG.

ABSTRACT:

Purpose

We previously reported that ∼30% of patients with localized follicular lymphoma (FL) staged by ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography receiving primary radiation therapy (RT) will relapse within 5 years. We sought to report outcomes for those who relapsed.

Methods and materials

We conducted a multicenter, retrospective study of patients aged ≥18 years who received RT ≥ 24 Gy for stage I to II, grade 1 to 3A FL, staged with ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography-computed tomography. Observation was defined as >6 months without treatment from relapse. Overall survival (OS) and freedom from progression (FFP) were estimated with Kaplan-Meier analysis and univariable and multivariable

SUBMITTER: Binkley MS 

PROVIDER: S-EPMC8162056 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature