De Novo Sequencing Provides Insights Into the Pathogenicity of Foodborne Vibrio parahaemolyticus.

ABSTRACT: Vibrio parahaemolyticus is a common pathogenic marine bacterium that causes gastrointestinal infections and other health complications, which could be life-threatening to immunocompromised patients. For the past two decades, the pathogenicity of environmental V. parahaemolyticus has increased greatly, and the genomic change behind this phenomenon still needs an in-depth exploration. To investigate the difference in pathogenicity at the genomic level, three strains with different hemolysin expression and biofilm formation capacity were screened out of 69 environmental V. parahaemolyticus strains. Subsequently, 16S rDNA analysis, de novo sequencing, pathogenicity test, and antibiotic resistance assays were performed. Comparative genome-scale interpretation showed

SUBMITTER: Liu J 

PROVIDER: S-EPMC8162212 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature