Mental Component Score (MCS) from Health-Related Quality of Life Predicts Incidence of Dementia in U.S. Males.

ABSTRACT:

Background

The Medical Outcomes Study Questionnaire Short Form 36 health survey (SF-36) measures health-related quality of life (HRQoL) from the individual's point of view and is an indicator of overall health status.

Objective

To examine whether HRQoL shows differential changes over time prior to dementia onset and investigate whether HRQoL predicts incidence of dementia.

Design

Prevention of Alzheimer's Disease (AD) by Vitamin E and Selenium (PREADViSE) trial, which recruited 7,547 non-demented men between 2002 and 2009. A subset of 2,746 PREADViSE participants who completed up to five SF-36 assessments at annual visits was included in the current analysis.

Setting

Secondary data analysis of PREADViSE data.

Participants

A subset of 2,746 PREADViSE part

SUBMITTER: Ding X 

PROVIDER: S-EPMC8162937 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature