Resting and postprandial serum bile acid concentrations in dogs with liver disease.

ABSTRACT:

Background

Serum bile acids (SBAs) are frequently measured in dogs. However, there is limited data comparing SBAs in different liver diseases diagnosed according to standardized histological criteria.

Objectives

To compare resting and postprandial SBAs, and determine their sensitivity and specificity, for various liver diseases in dogs.

Animals

Three hundred and forty-one client-owned dogs with suspected liver disease that had a liver biopsy and SBAs measured.

Methods

Multicenter retrospective study. Cases were classified according to standardized histological criteria. The sensitivity and specificity of resting and postprandial SBAs for the diagnosis of each liver disease, and all liver diseases combined, were calculated.

Results

The median resting SBAs

SUBMITTER: Pena-Ramos J 

PROVIDER: S-EPMC8163115 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature