Triazole-based osmium(ii) complexes displaying red/near-IR luminescence: antimicrobial activity and super-resolution imaging.

ABSTRACT: Cellular uptake, luminescence imaging and antimicrobial activity against clinically relevant methicillin-resistant S. aureus (MRSA) bacteria are reported. The osmium(ii) complexes [Os(N^N)₃]²⁺ (N^N = 1-benzyl-4-(pyrid-2-yl)-1,2,3-triazole (1 ²⁺); 1-benzyl-4-(pyrimidin-2-yl)-1,2,3-triazole (2 ²⁺); 1-benzyl-4-(pyrazin-2-yl)-1,2,3-triazole (3 ²⁺)) were prepared and isolated as the chloride salts of their meridional and facial isomers. The complexes display prominent spin-forbidden ground state to triplet metal-to-ligand charge transfer (³MLCT) state absorption bands enabling excitation as low as 600 nm for fac/mer-3 ²⁺ and observation of emi

SUBMITTER: Smitten KL 

PROVIDER: S-EPMC8163367 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature