Early diet in preterm infants and later cognition: 10-year follow-up of a randomized controlled trial.

ABSTRACT:

Background

Achieving adequate nutrition in preterm infants is challenging. The post-discharge period may be critical for influencing growth and cognitive outcomes. We studied the effects of post-discharge nutrition on childhood cognition.

Methods

Preterm-born children were randomized at ~36 weeks corrected age (CGA) to either preterm formula (PTF) or term formula (TF) until 6 months, or PTF until 40 weeks CGA, then TF until 6 months (crossover group). Childhood cognition was assessed using the short form Wechsler Intelligence Scale for Children III, allowing computation of full-scale intelligence quotient (FSIQ) and four-factor index scores; verbal comprehension, freedom from distractibility (FDI), perceptual organization (POI), and processing speed (PSI).

Results

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SUBMITTER: Embleton ND 

PROVIDER: S-EPMC8163596 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature