Detection of mink astrovirus in Poland and further phylogenetic comparison with other European and Canadian astroviruses.

ABSTRACT: Mink astrovirus infection remains a poorly understood disease entity, and the aetiological agent itself causes disease with a heterogeneous course, including gastrointestinal and neurological symptoms. This paper presents cases of astrovirus infection in mink from continental Europe. RNA was isolated from the brains and intestines of animals showing symptoms typical of shaking mink syndrome (n = 6). RT-PCR was used to amplify astrovirus genetic material, and the reaction products were separated on a 1% agarose gel. The specificity of the reaction was confirmed by sequencing fragment coding RdRP protein (length of sequencing product 170 bp) from all samples. The presence of astrovirus RNA was detected in each of the samples tested. Sequencing and bioinformatic analysis indicated the presenc

SUBMITTER: Jakubczak A 

PROVIDER: S-EPMC8164600 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature