Muscle-strengthening activities and cancer incidence and mortality: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Physical activity has been associated with reduced risk of seven types of cancer. It remains unclear, however, whether muscle-strengthening activities also reduce cancer incidence and mortality.

Methods

PubMed, Embase, Web of Science and Scopus were searched from inception to March 2020. Summary hazard ratio (HR) and 95% confidence intervals (CI) were estimated using random-effects models.

Results

Twelve studies (11 cohorts; 1 case-control), 6 to 25 years of follow-up, including 1,297,620 participants, 32,196 cases and 31,939 deaths, met inclusion criteria. Muscle-strengthening activities were associated with a 26% lower incidence of kidney cancer (HR for high vs low levels of muscle-strengthening activities: 0.74; 95% CI 0.56 to 0.98; I² 0%; 2 s

SUBMITTER: Nascimento W 

PROVIDER: S-EPMC8164763 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature