Trajectories of cognitive performance over five years in a prospective cohort of patients with breast cancer (NEON-BC).

ABSTRACT:

Purpose

To identify trajectories of cognitive performance up to five years since diagnosis and their predictors, in a cohort of patients with breast cancer (BCa).

Methods

A total of 464 women with BCa admitted to the Portuguese Institute of Oncology, Porto, during 2012, were evaluated with the Montreal Cognitive Assessment (MoCA) before any treatment, and after one, three and five years. Probable cognitive impairment (PCI) at baseline was defined based on normative age- and education-specific reference values. Mclust was used to define MoCA trajectories. Receiver Operating Characteristic curves were used to assess the predictive accuracy for cognitive trajectories.

Results

Two trajectories were identified, one with higher scores and increasing overtime, and the other,

SUBMITTER: Araujo N 

PROVIDER: S-EPMC8165446 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature