A novel c.-652C>T mutation in UCHL1 gene is associated with the growth performance in Yangzhou goose.

ABSTRACT: As a member of the ubiquitin-dependent proteasome degradation pathway, Ubiquitin carboxyl-terminal hydrolase-L1 (UCHL1) plays a key role in post-translational modification and protein degradation, and it is extensive and important for the regulation of various biological functions of the organism. However, its function remains unclear in goose growth performance. In this study, the full-length genomic DNA and coding region of UCHL1 gene was firstly cloned and characterized in Yangzhou goose. Tissue expression profile revealed that UCHL1 was exclusively expressed in brain and gonads. A novel single nucleotide polymorphisms c.-652C>T which is significantly related to 64-d body weight of Yangzhou goose was found in UCHL1 promoter region by comparative sequencing. Correlation analysis in a pop

SUBMITTER: Wang Q 

PROVIDER: S-EPMC8165569 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature