Association of eleven single nucleotide polymorphisms with refractive disorders from Eskisehir, Turkey.

ABSTRACT:

Aim

To investigate relationship between refractive errors and eleven single nucleotide polymorphisms (SNPs) in HGF, GC, MFN1, GNB4, and VDR genes in Turkish population.

Methods

A group of 212 participants with myopia (n=91), hyperopia (n=45), and emmetropia (n=76) were investigated in this study. SNPs in HGF, GC, MFN1, GNB4 and VDR genes were studied by SnapShot technique.

Results

The patients in this study consists of 47 female/44 male (age: 23.47±4.30) patients with myopia, 20 female/25 male (age: 31.20±8.02) with hyperopia and 33 female/43 male (age: 25.22±6.60) with emmetropia. The genotype distribution of the rs7618348 polymorphism, which was the only statistically significant one between myopia and emmetropia grou

SUBMITTER: Unlu N 

PROVIDER: S-EPMC8165615 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature