Initial and Recurrent Hyperkalemia Events in Patients With CKD in Older Adults: A Population-Based Cohort Study.

ABSTRACT:

Background

The risk of hyperkalemia is elevated in chronic kidney disease (CKD); however, the initial and recurrent risk among older individuals is less clear.

Objectives

We set out to examine the initial and 1-year recurrent risk of hyperkalemia by level of kidney function (estimated glomerular filtration rate, eGFR) in older adults (≥66 years old).

Design

Population-based, retrospective cohort study.

Settings

Ontario, Canada.

Participants

905 167 individuals (≥66 years old) from 2008 to 2015.

Measurements

Serum potassium values.

Methods

Individuals were stratified by eGFR (≥90, 60-89, 30-59, 15-29 mL/min/1.73 m²) and examined for the risk of incident hyperkalemia (K ≥ 5.5 mEq/L) using adjusted Cox proportional hazards models. T

SUBMITTER: Sriperumbuduri S 

PROVIDER: S-EPMC8165829 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature