The holobiont transcriptome of teneral tsetse fly species of varying vector competence.

ABSTRACT:

Background

Tsetse flies are the obligate vectors of African trypanosomes, which cause Human and Animal African Trypanosomiasis. Teneral flies (newly eclosed adults) are especially susceptible to parasite establishment and development, yet our understanding of why remains fragmentary. The tsetse gut microbiome is dominated by two Gammaproteobacteria, an essential and ancient mutualist Wigglesworthia glossinidia and a commensal Sodalis glossinidius. Here, we characterize and compare the metatranscriptome of teneral Glossina morsitans to that of G. brevipalpis and describe unique immunological, physiological, and metabolic landscapes that may impact vector competence differences between these two species.

Results

An active expression profile was observed for Wigglesworthia imme

SUBMITTER: Medina Munoz M 

PROVIDER: S-EPMC8166097 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature