Perspective: Application of N-of-1 Methods in Personalized Nutrition Research.

ABSTRACT: Personalized and precision nutrition aim to examine and improve health on an individual level, and this requires reconsideration of traditional dietary interventions or behavioral study designs. The limited frequency of measurements in group-level human nutrition trials cannot be used to infer individual responses to interventions, while in behavioral studies, retrospective data collection does not provide an accurate measure of how everyday behaviors affect individual health. This review introduces the concept of N-of-1 study designs, which involve the repeated measurement of a health outcome or behavior on an individual level. Observational designs can be used to monitor a participant's usual health or behavior in a naturalistic setting, with repeated measurements conducted in real time

SUBMITTER: Potter T 

PROVIDER: S-EPMC8166550 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature