Quantitative Checklist for Autism in Toddlers (Q-CHAT). A population screening study with follow-up: the case for multiple time-point screening for autism.

ABSTRACT:

Objective

This is a prospective population screening study for autism in toddlers aged 18-30 months old using the Quantitative Checklist for Autism in Toddlers (Q-CHAT), with follow-up at age 4.

Design

Observational study.

Setting

Luton, Bedfordshire and Cambridgeshire in the UK.

Participants

13 070 toddlers registered on the Child Health Surveillance Database between March 2008 and April 2009, with follow-up at age 4; 3770 (29%) were screened for autism at 18-30 months using the Q-CHAT and the Childhood Autism Spectrum Test (CAST) at follow-up at age 4.

Interventions

A stratified sample across the Q-CHAT score distribution was invited for diagnostic assessment (phase 1). The 4-year follow-up included the CAST and the Checklist for Referral (CFR). All wi

SUBMITTER: Allison C 

PROVIDER: S-EPMC8166626 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature