Neurodevelopmental origins of self-limiting rolandic epilepsy: Systematic review of MR imaging studies.

ABSTRACT:

Objective

Recent neuroimaging studies have revealed differences in cortical and white matter brain structure in children with self-limiting rolandic epilepsy (RE). Despite this, reproducibility of the findings has been difficult, and there is no consensus about where and when structural differences are most apparent. We performed a systematic review of quantitative neuroimaging studies in children with RE to explore these questions.

Methods

Using PRISMA guidelines, we used a multilayered search strategy to identify neuroimaging studies in RE. Publications were included if they were quantitative and derived from controlled group studies and passed a quality assessment. Findings of the studies were presented and stratified by duration of epilepsy and age of participants.

Re

SUBMITTER: Smith SDW 

PROVIDER: S-EPMC8166787 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature