Disease burden and economic impact of diagnosed non-alcoholic steatohepatitis (NASH) in the United Kingdom (UK) in 2018.

ABSTRACT:

Background and aims

Non-alcoholic steatohepatitis (NASH) - a progressive subset of non-alcoholic fatty liver disease (NAFLD) - is a chronic liver disease that can progress to advanced fibrosis, cirrhosis, and end-stage liver disease (ESLD) if left untreated. Early-stage NASH is usually asymptomatic, meaning a large proportion of the prevalent population are undiagnosed. Receiving a NASH diagnosis increases the probability that a patient will receive interventions for the purpose of managing their condition. The purpose of this study was to estimate the disease burden and economic impact of diagnosed NASH in the United Kingdom (UK) adult population in 2018.

Methods

The socioeconomic burden of diagnosed NASH from a societal perspective was estimated using cost-of-illness metho

SUBMITTER: Morgan A 

PROVIDER: S-EPMC8166804 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature