Percolation networks inside 3D model of the mineralized collagen fibril.

ABSTRACT: Bone is a hierarchical biological material, characterized at the nanoscale by a recurring structure mainly composed of apatite mineral and collagen, i.e. the mineralized collagen fibril (MCF). Although the architecture of the MCF was extensively investigated by experimental and computational studies, it still represents a topic of debate. In this work, we developed a 3D continuum model of the mineral phase in the framework of percolation theory, that describes the transition from isolated to spanning cluster of connected platelets. Using Monte Carlo technique, we computed overall 120 × 10⁶ iterations and investigated the formation of spanning networks of apatite minerals. We computed the percolation probability for different mineral volume fractions characteristic of human bone

SUBMITTER: Bini F 

PROVIDER: S-EPMC8166932 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature