Determination of adrenal hypersecretion in primary Aldosteronism without aldosterone-production adenomas.

ABSTRACT:

Background

Primary aldosteronism (PA) is highly prevalent in hypertensive population. Adrenal vein sampling (AVS) is the only procedure to assess adrenal aldosterone hypersecretion in PA. PA patients without aldosterone-producing adenomas (APA) frequently have unilateral aldosterone hypersecretion (UAH). These patients could bear inappropriate adrenalectomy without AVS. This study aims to identify which clinical characteristics should be recommended to perform AVS in these PA patients.

Methods

This study was performed from January 2018 to July 2019 at a center for hypertension and metabolic diseases. Adrenal computed tomography (CT) scan, biochemical evaluation, and AVS were performed.

Results

Total 141 patients were included in this study. Aldosterone to renin ratio

SUBMITTER: Sun F 

PROVIDER: S-EPMC8167985 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature