Racial Differences in Population Attributable Risk for Epithelial Ovarian Cancer in the OCWAA Consortium.

ABSTRACT:

Background

The causes of racial disparities in epithelial ovarian cancer (EOC) incidence remain unclear. Differences in the prevalence of ovarian cancer risk factors may explain disparities in EOC incidence among African American (AA) and White women.

Methods

We used data from 4 case-control studies and 3 case-control studies nested within prospective cohorts in the Ovarian Cancer in Women of African Ancestry Consortium to estimate race-specific associations of 10 known or suspected EOC risk factors using logistic regression. Using the Bruzzi method, race-specific population attributable risks (PAR) were estimated for each risk factor individually and collectively, including groupings of exposures (reproductive factors and modifiable factors). All statistical tests were 2-si

SUBMITTER: Peres LC 

PROVIDER: S-EPMC8168275 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature