Understanding the role of left and right ventricular strain assessment in patients hospitalized with COVID-19.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) can cause cardiac injury resulting in abnormal right or left ventricular function (RV/LV) with worse outcomes. We hypothesized that two-dimensional (2D) speckle-tracking assessment of LV global longitudinal strain (GLS) and RV free wall strain (FWS) by transthoracic echocardiography can assist as markers for subclinical cardiac injury predicting increased mortality.

Methods

We performed 2D strain analysis via proprietary software in 48 patients hospitalized with COVID-19. Clinical information, demographics, comorbidities, and lab values were collected via retrospective chart review. The primary outcome was in-hospital mortality based on an optimized abnormal LV GLS value via ROC analysis and RV FWS.

Results

The optimal LV

SUBMITTER: Park J 

PROVIDER: S-EPMC8168299 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature