Evaluation of the AMP SARS-CoV-2 rapid antigen test in a hospital setting.

ABSTRACT:

Objectives

Quick and inexpensive SARS-CoV-2 screening and frontline testing are in growing demand. Our study aimed to evaluate the performance of the immunochromatographic AMP rapid antigen test (AMP RAT) compared to the gold-standard real-time reverse transcription PCR (rRT-PCR) in a hospital cohort.

Methods

A total of 392 patients, who presented consecutively with COVID-19 symptoms in our emergency department, were included in this retrospective study. Two swabs were collected per patient: a nasopharyngeal for the RAT and a combined naso- and oropharyngeal for the rRT-PCR. A positive rRT-PCR (defined as cycle threshold (Ct) < 40) was found in 94 (24%) patients.

Results

In our cohort with a median patient age of 70, overall sensitivity and specificity of the AMP RAT

SUBMITTER: Leixner G 

PROVIDER: S-EPMC8168346 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature