Effects of dietary macronutrients on serum urate: results from the OmniHeart trial.

ABSTRACT:

Background

Dietary recommendations to prevent gout emphasize a low-purine diet. Recent evidence suggests that the Dietary Approaches to Stop Hypertension (DASH) diet reduces serum urate while also improving blood pressure and lipids.

Objective

To compare the effects of DASH-style diets emphasizing different macronutrient proportions on serum urate reduction.

Methods

We conducted a secondary analysis of the Optimal Macronutrient Intake Trial to Prevent Heart Disease feeding study, a 3-period, crossover design, randomized trial of adults with prehypertension or hypertension. Participants were provided with 3 DASH-style diets in random order, each for 6 wk. Each DASH-style diet emphasized different macronutrient proportions: a carbohydrate-rich (CARB) diet, a protein-ric

SUBMITTER: Belanger MJ 

PROVIDER: S-EPMC8168362 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature