DNA-polymer conjugates via the graft-through polymerisation of native DNA in water.
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ABSTRACT:
SUBMITTER: Arkinstall LA
PROVIDER: S-EPMC8168459 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Publications
DNA-polymer conjugates <i>via</i> the graft-through polymerisation of native DNA in water.
Arkinstall Lucy A LA Husband Jonathan T JT Wilks Thomas R TR Foster Jeffrey C JC O'Reilly Rachel K RK
Chemical communications (Cambridge, England) 20210601 44
The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases. ...[more]
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