DNA-polymer conjugates via the graft-through polymerisation of native DNA in water.

ABSTRACT: The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases.

SUBMITTER: Arkinstall LA 

PROVIDER: S-EPMC8168459 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature