Associations Between Retinal Artery/Vein Occlusions and Risk of Vascular Dementia.

ABSTRACT:

Background

Vascular disease is a risk factor for Alzheimer's disease (AD) and related dementia in older adults. Retinal artery/vein occlusion (RAVO) is an ophthalmic complication of systemic vascular pathology. Whether there are associations between RAVO and dementia risk is unknown.

Objective

To determine whether RAVOs are associated with an increased risk of developing vascular dementia or AD.

Methods

Data from Adult Changes in Thought (ACT) study participants were analyzed. This prospective, population-based cohort study followed older adults (age ≥65 years) who were dementia-free at enrollment for development of vascular dementia or AD based on research criteria. RAVO diagnoses were extracted from electronic medical records. Cox-regression survival analyses were s

SUBMITTER: Lee CS 

PROVIDER: S-EPMC8168611 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature