A novel approach to evaluate the effects of artificial bone focal lesion on the three-dimensional strain distributions within the vertebral body.

ABSTRACT: The spine is the first site for incidence of bone metastasis. Thus, the vertebrae have a high potential risk of being weakened by metastatic tissues. The evaluation of strength of the bone affected by the presence of metastases is fundamental to assess the fracture risk. This work proposes a robust method to evaluate the variations of strain distributions due to artificial lesions within the vertebral body, based on in situ mechanical testing and digital volume correlation. Five porcine vertebrae were tested in compression up to 6500N inside a micro computed tomography scanner. For each specimen, images were acquired before and after the application of the load, before and after the introduction of the artificial lesions. Principal strains were computed within the bone by means of digital

SUBMITTER: Palanca M 

PROVIDER: S-EPMC8168867 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature