Mechanistic model of nutrient uptake explains dichotomy between marine oligotrophic and copiotrophic bacteria.

ABSTRACT: Marine bacterial diversity is immense and believed to be driven in part by trade-offs in metabolic strategies. Here we consider heterotrophs that rely on organic carbon as an energy source and present a molecular-level model of cell metabolism that explains the dichotomy between copiotrophs-which dominate in carbon-rich environments-and oligotrophs-which dominate in carbon-poor environments-as the consequence of trade-offs between nutrient transport systems. While prototypical copiotrophs, like Vibrios, possess numerous phosphotransferase systems (PTS), prototypical oligotrophs, such as SAR11, lack PTS and rely on ATP-binding cassette (ABC) transporters, which use binding proteins. We develop models of both transport systems and use them in proteome allocation problems to predict the optim

SUBMITTER: Norris N 

PROVIDER: S-EPMC8168909 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature