Cognitive Trajectories in Comorbid Dementia With Schizophrenia or Bipolar Disorder: The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register.

ABSTRACT:

Objectives

We aimed to compare trajectories of cognitive performance in individuals diagnosed with dementia with and without severe mental illness (SMI).

Design

Retrospective cohort study.

Setting

We used data from a large longitudinal mental healthcare case register, the Clinical Record Interactive Search (CRIS), at the South London and Maudsley NHS Foundation Trust (SLaM) which provides mental health services to four south London boroughs.

Participants

Our sample (N = 4718) consisted of any individual who had a primary or secondary diagnosis of dementia from 2007 to 2018, was 50 years old or over at first diagnosis of dementia and had at least 3 recorded Mini-Mental State Examination (MMSE) scores.

Measurements

Cognitive performance was measured using

SUBMITTER: Bendayan R 

PROVIDER: S-EPMC8169045 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature