Femoral-popliteal peripheral artery disease: From symptom presentation to management and treatment controversies.

ABSTRACT: Peripheral artery disease (PAD) is a common condition with increasing prevalence domestically and worldwide. Patients with PAD have a poor prognosis, as PAD is associated with high rates of myocardial infarction, ischemic stroke, and cardiovascular disease death. The primary symptom of PAD, claudication, significantly reduces quality of life and functional status and is associated with depression. In addition to several advances in medications for PAD over the last decade, endovascular device therapy has seen a significant breakthrough in the form of paclitaxel-coated devices (PCDs), which significantly reduce rates of restenosis relative to non-PCDs, a finding which has been demonstrated in numerous randomized clinical trials. After their introduction to the market in 2012 (paclitaxel-elu

SUBMITTER: Krawisz AK 

PROVIDER: S-EPMC8169531 | biostudies-literature | 2021 Mar-Apr

REPOSITORIES: biostudies-literature