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Exercise right ventricular ejection fraction predicts right ventricular contractile reserve.


ABSTRACT:

Background

Right ventricular (RV) contractile reserve shows promise as an indicator of occult RV dysfunction in pulmonary vascular disease. We investigated which measure of RV contractile reserve during exercise best predicts occult RV dysfunction and clinical outcomes.

Methods

We prospectively studied RV contractile reserve in 35 human subjects referred for right heart catheterization for known or suspected pulmonary hypertension. All underwent cardiac magnetic resonance imaging, echocardiography, and supine invasive cardiopulmonary exercise testing with concomitant RV pressure-volume catheterization. Event-free survival was prospectively adjudicated from time of right heart catheterization for a 4-year follow-up period.

Results

RV contractile reserve during exercise

SUBMITTER: Ireland CG 

PROVIDER: S-EPMC8169559 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature