Right ventricular insertion promotes reinitiation of ventricular fibrillation in defibrillation failure.

ABSTRACT:

Background

Shocks near defibrillation threshold (nDFT) strength commonly extinguish all ventricular fibrillation (VF) wavefronts, but a train of rapid, well-organized postshock activations (PAs) typically appears before sinus rhythm ensues. If one of the PA waves undergoes partial propagation block (wavebreak), reentry may be induced, causing VF to reinitiate and the shock to fail.

Objective

The purpose of this study was to determine whether wavebreak leading to VF reinititation following nDFT shocks occurs preferentially at the right ventricular insertion (RVI), which previous studies have identified as a key site for wavebreak.

Methods

We used panoramic optical mapping to image the ventricular epicardium of 6 isolated swine hearts during nDFT defibrillation episodes

SUBMITTER: Iijima K 

PROVIDER: S-EPMC8169561 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature